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In Vitro
Fertilization,
literally
meaning
'fertilization
in a glass', is
a treatment for
infertility
where a woman
has failed to
respond to other
medical and
surgical
interventions.
The world's
first IVF baby
was born in 1978
and over one
million babies
have been born
as a result of
IVF since then.
At
ivfmiraclebaby
we have had
great success
using IVF with
mature women who
are unable to
conceive
naturally, as
well as for
other causes of
infertility. We
have seen the
wonder of this
procedure and
the gift of new
life it has
presented to so
many couples.
There are many
other causes of
infertility
which can be
helped with the
use of IVF
including:
-Both fallopian
tubes are absent
or blocked due
to surgery,
tubal pregnancy,
or infections
such as STD.
-other
treatments such
as ovulation
induction and
intra uterine
insemination
have proven
unsuccessful.
-unexplained
infertility
where all the
investigations
performed on the
couple are
normal, but they
still do not
conceive with
routine
treatments.
As long as a
woman has
functioning
ovaries they can
be stimulated to
produce mature
eggs that can be
fertilized. If
she has a
healthy uterus
the resultant
embryos can be
returned to her
uterus to
complete the
procedure. With
ICSI we only
need one healthy
sperm per egg to
create an
embryo. This
enables men with
a low sperm
count to father
his biological
children.
How IVF works
In order for
pregnancy to
occur naturally
an egg has to be
released from an
ovary and unite
with a sperm.
Normally this
occurs within
the fallopian
tube, which
connects the
uterus (womb) to
the ovary. In
IVF,
fertilization
occurs in a
laboratory after
eggs and sperm
have been
collected from
the parents or
donors. The
resultant
embryos are then
transferred into
the uterus to
grow into a
baby.
Dr Wiwat and his
team have
performed
thousands of IVF
procedures and
are expert in
determining the
correct time to
retrieve the
eggs. He has a
high rate of egg
retrieval and
patients rarely
experience side
effects.
The retrieval
procedure to
obtain the eggs
is performed
trans-vaginally
using a hollow
needle guided by
the ultrasound
image. Eggs are
gently removed
from the
ovaries. Timing
is crucial
because the egg
will not develop
properly if it
is collected too
early. If too
late, the egg
may develop
poorly or may
have already
been released
from the ovary
and lost.
The number of
mature eggs is
immediately
identified by
our experienced
embryologists
and the
fertilization
procedure
begins. In our
experience, ICSI
is the most
successful
method of
fertilization as
only the
healthiest sperm
are chosen to be
inserted into
the egg, one
sperm for one
egg. The result
once
fertilization
has occurred is
an embryo.
The embryo
becomes a
Blastocyst when
it has developed
to the point of
having 2
different cell
components and a
fluid cavity.
Human embryos,
in culture in an
IVF laboratory,
or developing
naturally in the
female body,
usually reach
the Blastocyst
stage by day 5
after
fertilization.
At
ivfMiraclebaby
we usually
perform embryo
transfer on the
fifth day of
development to
obtain the best
possible outcome
as only the
healthiest
embryos survive
until the 5th
day. A day 5
transfer with
IVF gives a high
pregnancy per
embryo success
rate.
Pre Implantation
Genetic
Diagnosis (PGD)
The quality of
the eggs is of
primary
importance to
create healthy
embryos. In
general, it is a
woman's age that
determines the
quality of her
eggs.
For the first
time women of
mature age (over
38) are able to
have their
embryos checked
using PGD to
select the
healthiest and
most robust
embryo. PGD is
done before the
embryo’s genetic
material becomes
‘active’, when
the cells inside
the embryo are
still all
identical and
each cell is
still capable of
becoming any
part of a baby.
This method does
not damage to
the developing
embryo.
Removal of two
cells when the
embryo is at the
8 cell stage
allows the
checking of
chromosomes for
abnormalities.
PGD for gender
selection can
also be done at
this time if the
couple want to
balance their
family. PGD will
be completed on
day 3 of embryo
development.
IVF has been
a miracle for
many women over
the last 30
years -giving
hope, joy and a
sense of
fulfillment that
was not an
option before.
We still feel a
sense of
excitement each
time this
miracle occurs.
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